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RTI International - Project Data Sphere Collaboration

Enriching Patient-Level Clinical Trial Data with Representative Socioeconomic Data

With funding support from the Robert Wood Johnson Foundation, Project Data Sphere (PDS) and RTI International collaborated to enhance the analytical utility of selected datasets hosted on data.ProjectDataSphere.org. Based on Patient Reported Outcomes data captured in the EQ-5D™ index score (derived from the EuroQOL five dimensions questionnaire), RTI identified likely corresponding socio-demographic, access, health, and healthcare related variables captured from the Medical Expenditure Panel Survey (MEPS). These variables include:

  • Socio-demographic factors: Age, race/ethnicity, sex, marital status, employment status, education level, income level, year in MEPS
  • Access related factors: Insurance coverage, ability to obtain necessary medical care
  • Health related: EQ5D, health status, work limitations, smoker status
  • Healthcare related: Office based physician visits, in-patient stays, ER visits, Rx purchases, total expenditures

Follow the links in the table below to view the data. You may view background information about each dataset without logging in; to view and download the dataset you must Apply for Access or Login if you are already an Authorized User. Supporting documents with additional information has been provided for each dataset. To access the MEPS data, please visit this link.

Original Patient-Level Dataset
Enhanced RTI Dataset
no longer available
A Phase 3, Randomized, Double-Blind, Multicenter Trial Comparing Orteronel (TAK-700) Plus Prednisone With Placebo Plus Prednisone in Patients With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer
no longer available
A Phase III, Randomized, Double-Blind, Multi-Center Parallel-Group Study to Assess the Efficacy of Vandetanib (ZACTIMA, ZD6474) versus Erlotinib (TARCEVA) in Patients With Locally Advanced or Metastatic (Stage IIIB - IV) Non-Small Cell Lung Cancer (NSCLC) after Failure of at least One Prior Cytotoxic Chemotherapy
no longer available
An International, Multi-Center, Randomized, Open-Label Study of PS-341Versus High-Dose Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma
no longer available
An Open-Label, Randomized Study of VELCADE®-Melphalan-Prednisone versus Melphalan-Prednisone in Subjects With Previously Untreated Multiple Myeloma