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A Double Blind Randomization to Letrozole or Placebo for Women Previously Diagnosed With Primary Breast Cancer Completing Five Years of Adjuvant Aromatase Inhibitor Either as Initial Therapy or After Tamoxifen (Including Those in The MA.17 Study)
Provider Data DescriptionThis dataset will allow users to reproduce the treatment comparison between letrozole group and the placebo group in trial NCT00754845.
SponsorCanadian Cancer Trials Group
Data ProviderNational Cancer Institute
Partial set or SubsetN/A
Patients in dataset1913
# of Patients Control954
# of Patients Experimental954
Clinical Trials.gov Information
Brief SummaryRATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. It is not yet known whether letrozole is more effective than a placebo in treating in women with breast cancer who have already received 5 years of aromatase inhibitor therapy.
PURPOSE: This randomized phase III trial is studying letrozole to see how well it works compared with a placebo in treating women with primary breast cancer who have received 5 years of aromatase inhibitor therapy.