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A Phase III Comparison of Hyperfractionated Radiation Therapy (RT) With BCNU and Conventional RT With BCNU for Supratentorial Malignant Glioma

Unique Dataset IDNCT03722355
SponsorRadiation Therapy Oncology GroupData ProviderNational Cancer InstituteTotal Study Enrolled Patients712RandomizationYesPubMed (PMID)29404979.0
Study PhaseClinical Study Phase IIIBlinding MethodOpen Label StudyType(s) of dataN/AIntervention TypeRadiation, DrugDataset TypeOther

Clinical Trial Title

A Phase III Comparison of Hyperfractionated Radiation Therapy (RT) With BCNU and Conventional RT With BCNU for Supratentorial Malignant Glioma

Trial Summary and Conditions

Hyperfractionated radiation therapy (RT) to 72.0 Gy with BCNU will be compared to conventional radiation therapy to 60.0 Gy with BCNU to determine if hyperfractionated RT can improve the median survival time of adults with supratentorial malignant gliomas.

Data Summary

See data dictionary for more details.

Study Objectives


Outcome Measures

Primary: Overall Survival [ Time Frame: From randomization to the date of death or last follow up, assessed up to 131 months. ]

Below are the clinical trial(s) associated with this dataset (all links are to ClinicalTrials.Gov):

NCI Description

This dataset will allow users to reproduce the treatment comparison between arm 1 and arm 2 in trial NCT03722355.

Available Downloads: NCT03722355-D1

To gain access to the data and analytic tools click here.

Data Dictionary: NCT03722355-D1-Data-Dictionary.pdf

DATA: NCT03722355-D1-Dataset.csv