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Type(s) of Cancer
CNS
Study Phase
Phase 3
Study Completion Date
1994-03-15
NCT03722355Uploaded 01-04-2019
Access via NCI by Request
PDS UID: nci-data-388
A Phase III Comparison of Hyperfractionated Radiation Therapy (RT) With BCNU and Conventional RT With BCNU for Supratentorial Malignant Glioma
Provider Information
Provider Data DescriptionThis dataset will allow users to reproduce the treatment comparison between arm 1 and arm 2 in trial NCT03722355.
SponsorRadiation Therapy Oncology Group
Data ProviderNational Cancer Institute
Clinical Trials.gov Information
Brief SummaryHyperfractionated radiation therapy (RT) to 72.0 Gy with BCNU will be compared to conventional radiation therapy to 60.0 Gy with BCNU to determine if hyperfractionated RT can improve the median survival time of adults with supratentorial malignant gliomas.
ConditionsGlioma
Glioblastoma Multiforme
Astrocytoma
Intervention TypeRadiation: Conventional RT
Radiation: Hyperfractionated RT
Drug: Carmustine
Drug(s)Drug: Carmustine
Total Enrolled712
RandomizationRandomized
Blinding MethodNone
Arms InterventionArm 1: Conventional RT + Carmustine - Active Comparator
Arm 2: Hyperfractionated RT + Carmustine - Experimental
Secondary IDN/A
PubMed (PMID)N/A
Collaborator(s)N/A
Region(s)N/A
Age Range18 Years and older (ADULT, OLDER_ADULT)
Files: NCT03722355-D1
Data DictionaryNCT03722355-D1-Data-Dictionary.pdf
DATANCT03722355-D1-Dataset.csv
OTHERREADME.pdf
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