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Type(s) of Cancer
CNS
Study Phase
Phase 3
Study Completion Date
2008
NCT00369785Uploaded 12-18-2019
Access via NCI by Request
PDS UID: nci-data-385
N/A
Provider Information
Provider Data DescriptionA total of 198 adult brain tumor survivors were randomly assigned to receive donepezil (5 mg for 6 weeks and 10 mg for 18 weeks) or placebo. Neurocognitive tests were assessed at baseline, 12 weeks post randomization, and 24 weeks post randomization. The primary aim of the study was to assess the effect of donepezil on a cognitive composite outcome (consisting of the average of eight standardized tests) at 24 weeks. A secondary aim was to assess the effect of donepezil on the individual tests. There was no significant effect of donepezil on the composite outcome. However, donepezil did significantly improve memory and motor speed/dexterity. This dataset contains all the data used in the publication PMID 25897156.
SponsorWake Forest University Health Sciences
Data ProviderNational Cancer Institute
Clinical Trials.gov Information
Brief SummaryN/A
ConditionsN/A
Intervention TypeDrug, Placebo
Drug(s)N/A
Total EnrolledN/A
RandomizationN/A
Blinding MethodN/A
Arms InterventionN/A
Secondary IDN/A
PubMed (PMID)N/A
Collaborator(s)N/A
Region(s)N/A
Age RangeN/A
Files: NCT00369785-D1
Data DictionaryNCT00369785-D1-Data-Dictionary.pdf
DATANCT00369785-D1-Dataset.csv
OTHERREADME.pdf
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