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A Phase III Study of Regional Radiation Therapy in Early Breast Cancer
Provider Data Descriptionheight and weight data
SponsorNCIC Clinical Trials Group
Data ProviderNational Cancer Institute
Clinical Trials.gov Information
Brief SummaryRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiation to the tumor site and surrounding area may kill more tumor cells. It is not yet known if radiation therapy to the breast alone following surgery is more effective than radiation therapy to the breast plus surrounding tissue in treating invasive breast cancer.
PURPOSE: This randomized phase III trial is studying radiation therapy to the breast alone to see how well it works compared to radiation therapy to the breast plus surrounding tissue in treating women who have undergone surgery for early-stage invasive breast cancer.
Intervention TypeRadiation: Standard Breast Irradiation Radiation: Breast Radiation plus Regional Radiation
Blinding MethodNone (Open Label)
Arms InterventionStandard Breast Irradiation - Active Comparator Breast Radiation plus regional radiation - Experimental
PubMed (PMID)26200977 31085285
Collaborator(s)National Cancer Institute (NCI) NSABP Foundation Inc Radiation Therapy Oncology Group Southwest Oncology Group Trans Tasman Radiation Oncology Group North Central Cancer Treatment Group
Age Range16 Years to 120 Years (Child, Adult, Older Adult)